Sr Manager, Portfolio and Program Management

Company: BioMarin Pharmaceutical Inc.
Location: Novato
Posted on: January 31, 2026

Job Description:

Who We Are BioMarin is a global biotechnology company that relentlessly pursues bold science to translate genetic discoveries into new medicines that advance the future of human health. Since our founding in 1997, we have applied our scientific expertise in understanding the underlying causes of genetic conditions to create transformative medicines, using a number of treatment modalities. Using our unparalleled expertise in genetics and molecular biology, we develop medicines for patients with significant unmet medical need. We enlist the best of the best – people with the right technical expertise and a relentless drive to solve real problems – and create an environment that empowers our teams to pursue bold, innovative science. With this distinctive approach to drug discovery, we’ve produced a diverse pipeline of commercial, clinical and preclinical candidates that have well-understood biology and provide an opportunity to be first-to-market or offer a substantial benefit over existing therapeutic options. About Technical Operations BioMarin’s Technical Operations group is responsible for creating our drugs for use in clinical trials and for scaling production of those drugs for the commercial market. These engineers, technicians, scientists and support staff build and maintain BioMarin’s cutting-edge manufacturing processes and sites, provide quality assurance and quality control to ensure we meet regulatory standards, and procure the needed goods and services to support manufacturing and coordinating the worldwide movement of our drugs to patients. Summary Novato Technical Services (NTS), part of Drug Substance Technologies (DST) in the Technical Development and Services (TDS) group is the technical partner for late-stage clinical and commercial operations and actively supports manufacturing processes throughout the product lifecycle. The NTS team owns the technical process for commercial products manufactured onsite and is accountable for its performance. We support production through robust process understanding, implementation of process improvement, constant monitoring of process performance, and process investigation and impact assessment when necessary. We ensure consistent high-quality supply of products to our patients and our mission is to lead the way in process science through innovation and excellence while maintaining the highest standards of quality and compliance. We are an inclusive, high-performing, highly motivated, and collaborative group looking for an innovative and passionate individual with strong business acumen and technical proficiency to become an integral part of our team. The Senior Manager is a senior leadership role responsible for driving portfolio governance, strategic alignment and execution excellence across a cross-functional organization. This role combines portfolio governance and people leadership, serving as a key partner to senior leaders. The role acts as a central point of co-ordination across functions, ensuring consistency in project management standards, transparent reporting, and continuous improvement of portfolio process. Key Responsibilities Support and execute end-to-end portfolio governance frameworks, including intake, prioritization, stage-gate process and decision forums. Lead and develop a team of portfolio, program and/or project management professionals Partner with leadership to ensure portfolio alignment with strategic objectives, funding, capacity, including risk management. Prepare materials and recommendations for portfolio review boards and steering committees. Lead components of annual and long-range portfolio planning. Facilitate scenarios and capacity analysis to support leadership decisions. Develop and maintain portfolio dashboards, KPIs, and executive level reports. Develop and enhance PMO processes, tools, and best practices, and implement global business processes for TDS, e.g. Technical Agenda and Consensus Yield. Developing detailed project plans and timelines for large scope cross-functional projects, driving execution and managing communication strategies, as needed Partner with data science team to develop a digital technical agenda to support TDS portfolio Mentor and train reports to build a team that can drive operational performance and deliver technical strategy for TDS Design, facilitate, and report out of workshops run for meeting business needs Design and execute on-site visual management and department engagement strategies Support organizational redesign efforts to align with TDS Portfolio centralization strategy. Represent TDS at governance bodies and technical network meetings . Facilitate portfolio reviews, steering committees, and governance meetings. Enable clear communication across cross functional teams and leadership. Other duties as assigned. Education Bachelor's degree in Life Sciences, Chemistry, Chemical Engineering or Pharmaceutical Engineering discipline requiredLean Six Sigma certification is strongly recommended Experience 10 years' experience in a cGMP regulated manufacturing environment, with exhibited knowledge or proficiency in a manufacturing or manufacturing support function (MSAT, process development, engineering, business ops, etc.) 7-10 years' experience in portfolio management, PMO, program or project management. Strong leadership, organizational, and management skills. Excellent verbal and written communication; ability to present and influence all levels, including executive leadership. Strong understanding of portfolio governance, resource management, and performance tracking. Advanced proficiency with portfolio and reporting tools (e.g. MS Project, Planview, PowerBI) Prior people management experience is preferred Ability to influence and drive cross-functional collaboration. Work Environment / Physical Demands Hybrid - would require 2-3 days onsite in Novato, CA This function will perform most of the work in an office setting, reviewing documents, participating in meetings, and authoring documents. This function may perform up to 60% of its functions at a computer terminal. The work environment characteristics described here are representative of those an employee encounters while performing the essential functions of this job. Reasonable accommodation may be made to enable individuals with disabilities to perform the essential functions. While performing the duties of this job, the employee is occasionally exposed to work near moving mechanical parts; fumes or airborne particles; toxic or caustic chemicals; high pressure and temperature utility systems, risk of electrical shock and vibration. The noise level in the work environment is usually moderate.The ability to perform gowning activities and enter the manufacturing plant is preferred but not required. Equipment This position requires ability to utilize a computer to perform tasks. Contacts This position will require interaction with multiple levels (from technicians up through executive management) in Quality Assurance, Quality Control, Manufacturing, Technical Development, Engineering, Regulatory Affairs, Accounting, Finance, and People Resources. Note: This description is not intended to be all-inclusive, or a limitation of the duties of the position. It is intended to describe the general nature of the job that may include other duties as assumed or assigned. Equal Opportunity Employer/Veterans/Disabled An Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability.

Keywords: BioMarin Pharmaceutical Inc., Livermore , Sr Manager, Portfolio and Program Management, Manufacturing , Novato, California